Premature Ovarian Insufficiency in Women Under 40

Women diagnosed with premature ovarian insufficiency before 40 face unique challenges, including health complications and mental health impacts, that interfere with natural life stages and overall well-being.

BODY CHANGESHORMONESPERIMENOPAUSESYMPTOMS

3/12/20252 min read

man in orange long sleeve shirt sitting on gray couch
man in orange long sleeve shirt sitting on gray couch

What is Premature Ovarian Insufficiency?

Premature ovarian insufficiency (POI) occurs when a woman's ovaries stop functioning normally before the age of 40. For many women facing this diagnosis, particularly those experiencing symptoms of perimenopause at such a young age, the challenges can be overwhelming. You may not have started your own family, and discovering that your body has begun its natural shutdown is HUGE. Not only can POI disrupt the reproductive years, but it often brings along a host of other health and emotional issues.

Factors That Trigger POI

There are various reasons why women may encounter premature ovarian insufficiency. Surgical interventions such as oophorectomy (removal of ovaries) can lead to a sudden onset of symptoms. Additionally, cancer treatments like chemotherapy or radiation can damage ovarian tissue, resulting in POI. Underlying conditions such as Turner syndrome or autoimmune diseases like lupus and thyroid disorders can also be culprits. Unfortunately, many women find themselves navigating these complexities alone, as POI is relatively under-discussed among health professionals and patients alike.

Seeking Help and Support

If you are in your 30's or early 40's whilst POI will affect your ability to have children naturally, you do have options. You may still be able to have children by using IVF and donated eggs from another woman donor or using your own eggs if you had some stored. If IVF is no longer an option then you might want to consider surrogacy and adoption.
POI brings with it the challenge of perimenopause symptoms even if you are not considering having a family in the future, these symptoms can seriously affect your mental health in the workplace and at home.
It's crucial for women who notice any change to their usual monthly rhythm, levels of tiredness or general mood to communicate with their general practitioner (GP) as they could be experiencing POI.

However, research by the Fawcett Society shows that nearly half of women haven't approached their GPs about their symptoms. It can sometimes feel more comfortable to direct questions to nursing staff, particularly in sensitive situations where discussing reproductive health feels daunting. Taking the first step to seek help can be life-changing. But there lies a concerning statistic: three in ten women have faced delays in receiving a diagnosis.

The Importance of Timely Treatment

When diagnosed with POI, timely treatment, such as hormone replacement therapy (HRT), can significantly improve quality of life. Regrettably, only four in ten women received HRT within an appropriate timeframe. Delayed treatment not only exacerbates physical symptoms like hot flashes and mood swings but also heightens feelings of anxiety and depression. Mental health is a critical aspect of managing POI, and understanding this connection sheds light on the importance of comprehensive care.

Final Thoughts

Women diagnosed with premature ovarian insufficiency face unique hurdles, particularly when it happens before 40. The interference with natural life stages, the potential health complications, and the mental health impacts combine to create a challenging situation. Awareness and open conversations about the condition can help ameliorate these struggles. If you or someone you know is experiencing symptoms, don’t hesitate to seek medical advice. Remember, reaching out to a GP or practice nurse is the first step toward navigating this complex journey.